First, we need to find out what happens if our body has a disease/disorder. When our body got attacked by any disease, the first reaction of our body is to try to fight itself without any external inputs or drugs.
This is where your immunity comes into play. Your immune system or immunity helps your body fight against many diseases or illnesses.
In biology, immunity is the ability to resist harmful microorganisms.
Immunity consists of specific and non-specific components.
The non-specific components act as barriers or elimination of a wide range of pathogens, regardless of their antigenic composition.
The specific components of the immune system adapt themselves to each new disease encountered and can generate pathogen-specific immunity.
Strong Immune system is theonly way to protect our body from the outside or from the harmful changes that occur within our body.
*The main tasks of the body’s immune system are:
- • To fight and eliminate pathogens such as bacteria, viruses, parasites, or fungi,
- To recognize and neutralize harmful substances from the environment,
- To Identify and neutralize harmful substances in the environment,
- To fight against pathogenic changes in the body, such as cancer cells.
What are the types of immunity?
The immune system plays a vital role in identifying and eliminating dangerous germs entering the bodybefore they cause any disease or damage.
There are two types of immunity:
- Innate Immune System
- Adaptive Immune System.
Innate Immune System
We are all born with some level of immunity against invaders. Human immune systems, like the systems of many animals, will attack foreign invaders from day one. This innate immunity encompasses our body’s external barriers - the first line of defence against pathogens - such as the skin and mucous membranes of the throat and intestine. If the pathogen succeeds in bypassing the innate immune system, adaptive or acquired immunity begins.
The native immune system is the first line of defense against pathogen invasion. They are also needed to initiate specific adaptive immune responses.
Indigenous immune systems rely on the body’s ability to recognize the preserved traits of pathogens not present in the unprotected host.
The innate immune system is an older evolutionary defense strategy and is the primary responsibility of the immune system found in primitive multicellular plants, fungi, insects, and multicellular organisms.
The major functions of the vertebrate innate immune system include:
- Recruiting immune cells to sites of infection through the production of chemical factors, including specialized chemical mediators called cytokines.
- Activation of the complement cascade to identify bacteria, activates cells, and promotes clearance of antibody complexes or dead cells.
- Activation of the complement cascade to identify bacteria activates cells and promotes clearance of antibody complexes or dead cells.
- Identification and removal of foreign substances present in organs, tissues, blood, and lymph, by specialized white blood cells.
- Activation of the adaptive immune system through a process known as antigen presentation.
- Act as a physical and chemical barrier to infectious agents; by physical measures such as bark or bark and chemical measures such as blood-typing factors or tree sap, which are released as a result of a bruise or other injury that crosses the physical barrier on the front line.
Adaptive Immune System
The adaptive immune system, also known as the acquired immune system, is a subsystem of the immune system composed of specialized cells and systemic processes that kill pathogens by inhibiting their growth.
Acquired immunity creates immunological memory after an initial response to a particular pathogen and results in an enhanced response to subsequent incidents with that pathogen. This process of acquired immunity is the basis of vaccination. Like the native system, the acquired system contains humoral immune components and cell-mediated immune components.
Immunity found in vertebrates is stimulated when a pathogen escapes the innate immune system and generates a threshold level of antigen and generates “strange” or “dangerous” signals activated by dendritic cells.
The major functions of the acquired immune system include:
- Recognition of specific “non-self” antigens in the presence of “self”, during the process of antigen presentation.
- Generation of responses that are tailored to maximally eliminate specific pathogens or pathogen-infected cells.
- Development of immunological memory, in which pathogens are “remembered” through memory B cells and memory T cells.
- In humans, it takes 4-7 days for the adaptive immune system to mount a significant response.
There are two types of adaptive immunity : Active and Passive.
- Active Immunity –Antibodies that develop in a person’s immune system after the body is exposed to an antigen through disease or when you get an immunization. This type of immunity lasts for a long time.
- Passive Immunity – Antibodies given to a person to prevent disease or to treat disease after the body is exposed to an antigen. Passive immunity is given from mother to child through the placenta before birth and through breast milk after birth. It can also be given medically through blood products that contain antibodies, such as immune globulin/plasma. This type of immunity is fast-acting but lasts only a few weeks or months.
Adaptive immunity can also be divided by the type of immune mediators involved; humoral immunity is the aspect of immunity that is mediated by secreted antibodies, whereas cell-mediated immunity involves T-lymphocytes alone
The immune system must be able to tell self from non-self. It does this by analysing or detecting the proteins found on the surface of cells. It learns to ignore its own or self-proteins at an early stage.
The immune system can be activated by many different things that the body does not recognize as its own. These are called antigens. Examples of antigens include proteins on the surface of bacteria, fungi, and viruses. When these antigens attach to special receptors on immune cells (cells of the immune system), a whole set of processes is stimulated in the body. When the body first comes into contact with a pathogen, it usually stores information about the microbe and how to fight it. Then, if he comes in contact with the germ again, he immediately recognizes the germ and may start fighting faster.
The cells in the body also have proteins on their surface. But these proteins usually do not stimulate the immune system to fight the cells. Sometimes the immune system mistakenly thinks that the body's cells are foreign. It then attacks healthy and unhealthy cells in the body. This is called an autoimmune response.
There are two types of immune responses:
- Humoral immunity - It is the aspect of immunity that is mediated by macromolecules found in extracellular fluids such as secreted antibodies, complement proteins, and certain antimicrobial peptides.
Humoral immunity is so named because it involves substances found in the humor or body fluids.
- Cell-mediated immunity - It is an immune response that does not involve antibodies. Rather, cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.
How to boost immunity?
Boosting immunityis creating a strong attention,
But to do so is not that simple for several reasons.
As the immune system is — a system, not a single entity.
Soto make it function well requires balance and harmony.
To best protect your body from harm, every component of your immune system needs to perform exactly according to plan.
The best way you can ensure that happens is to practice the good-for-you every day Several dietary and lifestyle changes may strengthen your body’s natural defences and help you fight harmful pathogens or disease-causing organisms.
First line of defence is to choose a healthy lifestyle.
Following general good-health guidelines is the single best step you can take toward naturally keeping your immune system strong and healthy. Every part of your body, including your immune system, functions better when protected from environmental assaults and bolstered by healthy-living strategies such as these:
- Don’t smoke :Like alcohol, smoking can also affect immune health. Anything that’s a toxin can compromise your immune system. The chemicals released by smoking — carbon monoxide, nicotine, nitrogen oxides, and cadmium — can interfere with the growth and function of immune cells, like cytokines, T cells, and B cells.
- Eat a diet high in fruits and vegetables :Several whole plant foods contain antioxidants, fiber, and vitamin C, all of which may lower your susceptibility to illness.
- Exercise regularly :Moderate exercise can reduce inflammation and promote the healthy turnover of immune cells. Jogging, biking, walking, swimming, and hiking are great options.
- Maintain a healthy weight, cut on added sugars: Added sugars contribute significantly to obesity, type 2 diabetes, and heart disease, all of which can suppress your immune system. Lowering your sugar intake may decrease inflammation and your risk of these conditions
- If you drink alcohol, drink only in moderation: Drinking high amounts of alcohol is associated with a range of negative health effects, including lowered immune function. When you drink high amounts of alcohol, your body is too busy trying to detoxify your system to bother with normal immune system function.
- Get adequate sleep: Inadequate sleep may increase your risk of getting sick. Most adults should get at least 7 hours of sleep per night.
- Try to minimize stress: Lowering your stress levels through meditation, yoga, exercise, and other practices can help keep your immune system functioning properly.
- Take steps to avoid infection : such as washing your hands frequently and cooking meats thoroughly.
How do nano curcumin & ginger extract help boost immunity?
Turmeric or Haldi has been used in India for thousands of years as a spice and medicinal purpose. Also, sometimes referred to as the Indian Saffron or Gold dust of Ayurveda, is beneficial in ways that scientists are still working on.
It has been used in the traditional Indian medicine system /Ayurveda for 4000 years.
The main components of Turmeric called Curcumin (turmeric extract) have potential medicinal properties and have been long used in the treatment of many major diseases. Curcumin has been widely researched and used for its Antiviral, anti-inflammatory, anti-oxidant, immune modulator, and anti-cancer properties for a very long time and has the potential of being a natural alternative for most degenerative diseases.
Since its discovery about two hundred years ago, curcumin has been one of the well-documented natural therapeutic ingredients. Many researchers believe that curcumin has more therapeutic potential than turmeric.
Curcumin, extracted from turmeric, is widely known for its anti-inflammatory properties that help boost immunity.
Researchers have found that curcumin stops the recruitment of specific immune cells which, when overactive, are linked to problems such as heart disease and obesity.
Studies also show that nano-emulsified curcumin or nano-curcumin stopped the recruitment of immune cells called macrophages that “eat up” the invasive pathogens but contribute to inflammation by obtaining pro-inflammatory chemicals.
As per studies, our body responds to a variety of factors that can lead to overactive native immune cells. Unfortunately, the overproduction of protein in the crisis leads to overactivity of these native cell types, which can be detrimental to our health. In addition, chronic activation of these proteins can lead to antiviral protections. Fortunately, several human studies have shown that curcumin supplementation reduces the blood levels of various crisis proteins. This research suggests that curcumin helps to normalize parts of the immune system that are normally overactive.
Curcumin has immune balancing properties that can be very helpful for people with chronic stress. In addition, curcumin helps promote optimal immune responses through its prebiotic-like properties, omega-3 stimulating ability, and anti-cortisol effects. Curcumin not only can improve the Anti-inflammatory, Antiviral, Antioxidant capacity or Enhance immune functions only but also has the potential of modulating the over the reactive immune response as an immune modulator.
Further, since turmeric/Curcumin is a fat-soluble compound, so as such its absorption into the body systems is quite less to fight dangerous and deadly diseases. So the nanotechnology applied to Curcumin, enhances its absorption to the levels where it can support and enhance our body’s fight against serious diseases.
More so there is unlimited scientific research data available as on date, on the beneficial effects of curcumin in the prevention and management of many deadly viral diseases, as it modulates most of the pathways, that lead the virus to replicate/multiply and cause multiple damages to the vital organs or the whole body as such.
Ginger, an aromatic spice that is indispensable in Indian kitchens, ginger has many medicinal and herbal values as well. It is often used as a home remedy for stomach aches, vomiting, flu, and the common cold.
Ginger extract has anti-inflammatory/antioxidant/antiviral properties that can help improve the body’s disease-fighting potential.
It also has anti-inflammatory and anti-oxidant properties to control the aging process.
In addition, it also has antimicrobial potential that can help treat infectious diseases. It is also a natural blood thinner and contains a phenolic anti-inflammatory compound called gingerol that may be responsible for relaxing blood vessels.